Identifying noise sources governing cell-to-cell variability
نویسندگان
چکیده
منابع مشابه
Cell-to-Cell Transcript Variability: Seeing Signal in the Noise
How stochastic is gene expression in mammalian cells? Not very, according to Battich et al., who report that single-cell variability in cytoplasmic mRNAs is remarkably predictable given measurements of a cell's phenotypic state and microenvironment. The noise from transcriptional bursts is buffered by a hallmark of eukaryotes-the nucleus.
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ژورنال
عنوان ژورنال: Current Opinion in Systems Biology
سال: 2018
ISSN: 2452-3100
DOI: 10.1016/j.coisb.2017.11.013